butabarbital will minimize the level or influence of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Outcome of coadministering a robust CYP3A4 inducer with fedratinib hasn't been studied.butabarbital will lessen the extent or influence of glecaprevir/pibrentasvir by impacting hepatic/intes